Ah yes, and here's where to get the two rare and expensive reagents (without having to buy them at exorbitant prices):
Nightshade is in the deepest part of Spiritwood, which lies a short distance southeast of Skara Brae. Search the coordinates I'J" by C'M" at midnight (It's marked by a group of trees much larger than all the ones surrounding it).
Mandrake Root is in the same spot as last time, a single swamp tile southeast of Minoc located at D'G" by L'G". Once again, you must search that spot at midnight.