We scavenge everything of value in Sweet's Factory and Duncan's Factory, clear the railroad tracks and head for the town of Snowman in search of Ana. Then it's time for - you guessed it - more grinding!
Ana's pretty awesome though, honestly. Learns nearly every Psi power in the game, gains a ton of Psi points and levels up at a quite frankly insane rate. The only downside is her relatively low HP and attack power.
